Chemical Name 1-Boc PiperazineMolecular Formula C9H18N2O2CAS Number 57260-71-6Molecular Weight 186.25 g/molIUPAC Name 1-(tert-Butoxycarbonyl)piperazineAppearance White crystalline powderMelting Point 88-92°CSolubility Soluble in dichloromethane, acetonitrile, THF; slightly soluble in waterGeneral Information 1-Boc Piperazine is a protected piperazine derivative used in synthetic and medicinal chemistry, particularly in the development of pharmaceuticals and peptides. The Boc group protects the piperazine nitrogen during reactions.Applications - Pharmaceutical synthesis - Peptide synthesis - Organic synthesis, especially in nitrogen-containing heterocyclesSynthetic Utility The Boc group in 1-Boc Piperazine protects the nitrogen during multi-step synthesis and can be removed under acidic conditions (e.g., TFA), allowing further reactions with the piperazine group.Handling and Safety Use PPE (gloves, goggles, lab coat). Store in a cool, dry place. Avoid moisture and handle in a well-ventilated area or fume hood.